OTHER NAMES(S): 3-carboxy-2-hydroxy-N, N, N-trimethyl-1-propanaminium inner salt, (3-carboxy2-hydroxypropyl) trimethylammonium hydroxide inner salt, 3-hydroxy-4-N-trimethylaminobutyrate, Aminocarnitine, B-hydroxy-N-trimethyl aminobutyric acid, Beta-hydroxy-gamma-trimethylammonium butyrate, Beta-hydroxyl-gamma-tributyl aminobutyrate, B(t) Factor, Carnitine, Carnitor, D-Carnitine, DL-Carnitine, Facteur B(t), L-3-hydroxy-4-(trimethylammonium)-butyrate, Levocarnitine, Lévocarnitine, Levocarnitine Fumurate, L-b-hydroxy-c-N-trimethylaminobutyric acid, L-Carnitina, L-Carnitine Fumarate, L-Carnitine L-Tartrate, L-Carnitine Tartrate, (R)-(3-carboxy-2-hydroxypropyl) trimethylammonium hydroxide, (R)-3-hydroxy-4-trimethylammonio-butyrate, Vitacarn, Vitamin B(t), Vitamine B(t).
L-Carnitine:
L-Carnitine is a naturally occurring compound in the body that plays a vital role in energy production and metabolism. It is a quaternary ammonium compound synthesized from the amino acids lysine and methionine. L-Carnitine is primarily responsible for transporting long-chain fatty acids into the mitochondria of cells, where they can be oxidized to generate energy.
Key functions of L-Carnitine include:
Energy production:
As mentioned earlier, L-Carnitine facilitates the transport of fatty acids into the mitochondria, where they undergo beta-oxidation to produce ATP (adenosine triphosphate), the primary energy currency of cells.
Fat metabolism:
L-Carnitine’s role in transporting fatty acids makes it essential for the metabolism of fats, which is particularly important during prolonged exercise or periods of fasting.
Heart health:
The heart relies heavily on fatty acid metabolism for energy production. L-Carnitine has been studied for its potential benefits in supporting heart health by improving energy production in heart muscle cells and reducing oxidative stress.
Exercise performance and recovery:
L-Carnitine supplements have been promoted as potential aids for exercise performance, as they may increase the use of fat for energy during workouts. Some studies have also suggested that L-Carnitine might reduce muscle damage and enhance recovery after intense exercise.
Brain function:
L-Carnitine may have a neuroprotective role and has been investigated for its potential benefits in various neurological conditions.
L-Carnitine is present in certain foods like red meat, fish, poultry, and dairy products. The body can also synthesize it naturally if it has enough essential amino acids. Additionally, L-Carnitine supplements are available, and they come in different forms, such as L-Carnitine tartrate and acetyl-L-Carnitine.
It’s important to note that while L-Carnitine is generally considered safe for most people when taken at appropriate dosages, it may interact with certain medications or medical conditions. As with any supplement, it’s best to consult with a healthcare professional before starting L-Carnitine supplementation, especially if you have any underlying health issues.
L-Carnitine Uses:
Weight Management:
L-Carnitine is often used as a supplement to aid in weight loss and fat burning. It is believed to enhance the use of fat for energy during exercise and physical activity, which may help individuals with weight management goals.
Sports Performance:
Athletes and active individuals may use L-Carnitine supplements to improve exercise performance and endurance. By increasing the utilization of fat for energy, it is thought to delay the onset of fatigue during prolonged physical activity.
Heart Health:
L-Carnitine has been studied for its potential benefits in supporting heart health. It may improve energy production in heart muscle cells, making it potentially beneficial for certain heart conditions such as angina and heart failure. However, more research is needed to establish its efficacy.
Male Infertility:
L-Carnitine has been investigated as a treatment for male infertility. It plays a role in sperm health and function, and some studies suggest that L-Carnitine supplementation could improve sperm quality.
Muscle Recovery:
Some research indicates that L-Carnitine supplementation might reduce muscle damage and inflammation after intense exercise, potentially aiding in muscle recovery and reducing exercise-induced muscle soreness.
Neurological Conditions:
L-Carnitine has been studied for its potential neuroprotective effects and its use in various neurological disorders. It has been explored as a treatment for conditions such as Alzheimer’s disease, dementia, and peripheral neuropathy. However, more research is needed in this area.
Chronic Fatigue Syndrome (CFS):
Some studies have investigated the use of L-Carnitine as a potential treatment for chronic fatigue syndrome, a condition characterized by persistent fatigue. While some research suggests potential benefits, more studies are required for conclusive evidence.
Vegan and Vegetarian Diets:
Individuals following strict vegan or vegetarian diets may consider L-Carnitine supplementation since it is primarily obtained from animal-derived sources in the diet.
It is important to note that while L-Carnitine shows promise in some of these areas, the scientific evidence is not always consistent, and its effectiveness may vary depending on individual factors. As with any supplement, it’s crucial to consult with a healthcare professional before using L-Carnitine, especially if you have any underlying health conditions or are taking medications. Additionally, it’s essential to use L-Carnitine as part of a balanced and healthy lifestyle, including a proper diet and regular exercise.
L-Carnitine Side Effects:
While L-Carnitine is generally considered safe for most people when taken at appropriate dosages, it may cause some side effects in certain individuals. The side effects of L-Carnitine can vary based on factors such as dosage, individual tolerance, and overall health. Some potential side effects of L-Carnitine include:
Gastrointestinal Disturbances:
Some people may experience mild gastrointestinal issues such as nausea, vomiting, diarrhea, or stomach cramps when taking L-Carnitine supplements.
Body Odor:
A specific type of L-Carnitine supplement called trimethylamine-N-oxide (TMAO) has been associated with a fishy body odor in some individuals.
Increased Appetite:
Some users have reported an increase in appetite as a side effect of L-Carnitine supplementation. This may counteract the weight loss effects that some people seek.
Allergic Reactions:
In rare cases, individuals may experience allergic reactions to L-Carnitine, which can manifest as itching, hives, swelling, or difficulty breathing. If any allergic symptoms occur, immediate medical attention is required.
Acidosis:
In individuals with certain metabolic disorders, high doses of L-Carnitine may lead to an increased risk of developing acidosis, a condition characterized by an imbalance of acid and base levels in the body.
Interactions with Medications:
L-Carnitine may interact with certain medications, particularly blood-thinning drugs like warfarin, and could potentially interfere with their effectiveness.
Seizures:
In rare cases, high doses of L-Carnitine have been associated with seizures, especially in individuals with a history of seizure disorders.
It’s essential to follow the recommended dosages and consult with a healthcare professional before starting L-Carnitine supplementation, especially if you have any pre-existing medical conditions or are taking medications. Pregnant or breastfeeding women should also seek medical advice before using L-Carnitine supplements.
As with any supplement, individual responses can vary, and some people may experience no side effects at all. However, if you experience any unusual or concerning symptoms while taking L-Carnitine, it is important to discontinue use and seek medical attention.
L-Carnitine Precautions:
When considering the use of L-Carnitine supplements, it’s essential to take certain precautions to ensure safe and effective usage. Here are some precautions to keep in mind:
Consult with a Healthcare Professional:
Before starting L-Carnitine supplementation, talk to your healthcare provider, especially if you have any underlying health conditions, are pregnant or breastfeeding, or are taking medications. They can evaluate your specific health status and determine if L-Carnitine is appropriate for you.
Dosage and Form:
Follow the recommended dosage instructions provided by your healthcare professional or the product label. Different forms of L-Carnitine supplements (e.g., L-Carnitine tartrate, acetyl-L-Carnitine) have different bioavailabilities and purposes, so use the specific form that aligns with your health goals.
Avoid High Doses:
Taking excessive amounts of L-Carnitine may lead to potential side effects, including gastrointestinal issues and other health concerns. Stick to the recommended dosage to minimize the risk of adverse effects.
Interactions with Medications:
Be aware of possible interactions between L-Carnitine and any medications you are currently taking. L-Carnitine may interact with certain drugs, particularly blood-thinning medications like warfarin. Inform your healthcare provider about all medications, supplements, and herbs you are using.
Medical Conditions:
If you have a history of seizures, liver or kidney problems, or other metabolic disorders, use L-Carnitine with caution and under the guidance of a healthcare professional.
Allergies:
If you have a known allergy to L-Carnitine or any of its components, avoid using L-Carnitine supplements.
Avoid Self-Diagnosis:
Do not use L-Carnitine as a substitute for medical treatments or to self-diagnose any health condition. Always seek professional medical advice for any health concerns.
Children and Elderly:
Extra caution should be exercised when considering L-Carnitine supplementation for children or elderly individuals. Dosages and suitability may vary based on age and health status.
Quality of Supplements:
Choose reputable brands when purchasing L-Carnitine supplements to ensure quality and safety. Look for products that have undergone third-party testing and adhere to good manufacturing practices (GMP).
Balanced Lifestyle:
L-Carnitine supplements should be viewed as a complement to a balanced diet and healthy lifestyle. They are not a magic solution for weight loss or other health issues.
Remember that individual responses to supplements can vary, and what works for one person may not work for another. If you experience any adverse effects while using L-Carnitine, discontinue use and seek medical advice. Always prioritize your overall health and well-being, and use supplements responsibly with guidance from healthcare professionals.
L-Carnitine Dosing:
The appropriate dosing of L-Carnitine can vary based on several factors, including age, health condition, purpose of supplementation, and the specific form of L-Carnitine being used. It’s crucial to follow the recommended dosages provided by healthcare professionals or the product label. Here are some general guidelines for L-Carnitine dosing based on different forms and purposes:
L-Carnitine Tartrate for General Use:
– Standard dosages for general use typically range from 500 mg to 2,000 mg per day.
– It is often divided into multiple doses throughout the day for better absorption.
– Some studies have used doses up to 3,000 mg per day, but higher doses may increase the risk of side effects.
Acetyl-L-Carnitine for Cognitive Function and Nervous System Support:
– Dosages for cognitive support typically range from 600 mg to 2,500 mg per day, divided into multiple doses.
– Higher doses (up to 3,000 mg per day) have been used in some studies for specific neurological conditions.
L-Carnitine L-Tartrate for Exercise Performance:
– Dosages for exercise performance enhancement usually range from 1,000 mg to 4,000 mg per day, split into multiple doses.
– It’s commonly taken 1 to 2 hours before exercise to potentially enhance fat utilization during physical activity.
Propionyl-L-Carnitine for Cardiovascular Support:
– Dosages for cardiovascular support range from 500 mg to 2,000 mg per day, in divided doses.
– Some studies have used higher doses (up to 4,000 mg per day) under medical supervision.
It’s crucial to start with lower doses and gradually increase if necessary while monitoring for any side effects. Individual responses to L-Carnitine can vary, so finding the optimal dosage may require some trial and error.
As always, it’s best to consult with a healthcare professional before starting L-Carnitine supplementation. They can provide personalized dosing recommendations based on your specific health needs and considerations. Pregnant or breastfeeding women, children, and individuals with certain medical conditions may require different dosages or should avoid L-Carnitine supplementation altogether.
FAQs
Is L-carnitine effective for fat loss?
Supplementation with L-carnitine can significantly reduce weight compared with those not taking supplements. However, the average weight loss is only less than 2 kilograms. Hence, supporting L-carnitine supplementation with diet and exercise would be the best way to achieve your weight goal.
Should I take L-carnitine every day?
Most people tolerate L-carnitine well. The recommended dosage is roughly 1–3 grams per day. However, people with genetic abnormalities or other conditions causing a lack of L-carnitine should talk to their doctor for a more specific dosage.
What is the use of L Carnicut?
L-Carnicut 3500 is essential for transporting long-chain fats into the cell (mitochondria). L-Carnitine taps into your fat supply and may provide support to burn it as fuel, resulting in increased energy.
Is L-carnitine good for females?
L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of this system to free radicals demand for advanced strategies to combat them
Does L-carnitine have side effects?
However, doses of approximately 3 g/day of carnitine supplements can cause nausea, vomiting, abdominal cramps, diarrhea, and a fishy body odor. It can also cause muscle weakness in people with uremia and seizures in those with seizure disorders.
Can I take L-carnitine if I don’t workout?
Yes, L-carnitine works without exercise too because it easily converts the fat into energy. The oxidised fatty acids are used as fuel and it is able to generate adenosine and triphosphate or ATP. So, L-carnitine does this cellular work when you both exercise and rest.
Is L-carnitine safe for kidneys?
It has been established that protein or LC supplementation or maximum protein intake cause renal damage. Several types of research have demonstrated no adverse effects of LC supplementation under its recommended dosages on kidney health.
Is L-carnitine tablets safe?
It has been used safely by mouth for up to 6 months. Underactive thyroid (hypothyroidism): Taking L-carnitine might make symptoms of hypothyroidism worse. Seizures: L-carnitine seems to make seizures more likely in people who have had seizures before. If you have had a seizure, don’t take L-carnitine.
How to use L-carnitine for best results?
While as little as 1 gram of L-carnitine can be effective, your best bet is to take 2-3 grams per dose for maximum benefit, along with at least 30-40 grams of carbs and 20-40 grams of protein, preferably with a meal. This applies if you take straight-up L-carnitine, L-carnitine L-tartrate, or propionyl-L-carnitine.
Does carnitine affect fertility?
L-carnitine is a supplement that comes from an amino acid, lysine, and is beneficial to many medical conditions. Of all the benefits, L-carnitine helps to improve the likelihood of fertility outcomes both in men and women.
Does L-carnitine increase fertility?
Decades of research show that carnitine, a compound found in animal proteins and synthesized in the human body to help support cellular health and energy production, plays a vital role in fertility.
Is L-carnitine good for sperm?
Analysis showed that carnitines significantly improve total sperm motility, progressive sperm motility and sperm morphology, but without effect on sperm concentration.
Can I take L-carnitine at night?
With meals: L-carnitine can be taken with a meal to aid in its absorption. In particular, taking L-Carnitine with carbohydrates as noted earlier in this article may be the most beneficial. Before bedtime: Taking L-carnitine before bedtime can help to support fat burning and muscle recovery during sleep.
What is the best time to take L-carnitine?
The best time to take L-carnitine supplements is generally either shortly before a meal or exercise. We recommend the acetyl-L-carnitine or glycine propionyl-L-carnitine forms if you plan on taking carnitine to improve athletic performance, cognitive function, and fat burning.
